Polyphenols proved to have antiallergic, antioxidative, antibacterial, and anti viral effects in in-vitro studies, but their high molecular weight made them less penetrable to the skin and cells. Oligonol®-CS contains low molecular weight oligomers, resulting in higher skin permeability.
Oligonol®-CS solution was used topically twice a day on left half of face, while a placebo was used on right half of face. Skin parameters such as skin elasticity, effect on noticeable pores, pigmentation, moisture and oil content, and wrinkles were measured at baseline and after 2 months.
In vivo and in vitro data reported that Oligonol®-CS:
“Based on these findings, Oligonol®-CS can be used as an active cosmetic ingredient with various functional activities for future cosmetic product development.”